Product overview:

PDIA3 (ERp57) mouse monoclonal antibody, clone LBI4D7

Field of research:

Antigen processing and presentation

Summary:

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq, Jul 2008]

Alternative names:

ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PDIA3

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 140-505 of human PDIA3(NP_005304) produced in E.coli.

Clone:

LBI4D7

Conjugation:

Unconjugated

Gene name:

protein disulfide isomerase family A member 3

Symbol:

PDIA3

Pathway:

Antigen processing and presentation

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com