Product overview:

UBE2J1 mouse monoclonal antibody, clone LBI2D4

Field of research:

Parkinson's disease, Ubiquitin mediated proteolysis

Summary:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Alternative names:

CGI-76; HSPC153; HSPC205; HSU93243; NCUBE-1; NCUBE1; UBC6; UBC6E; Ubc6p

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

UBE2J1

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human UBE2J1(NP_057105) produced in HEK293T cell.

Clone:

LBI2D4

Conjugation:

Unconjugated

Gene name:

ubiquitin conjugating enzyme E2 J1

Symbol:

UBE2J1

Pathway:

Parkinson's disease, Ubiquitin mediated proteolysis

Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com