Product overview:

SDCBP (Syntenin) mouse monoclonal antibody, clone LBI2H6

Field of research:

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Summary:

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Alternative names:

MDA-9; MDA9; ST1; SYCL; TACIP18

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SDCBP

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human SDCBP(NP_005616) produced in HEK293T cell.

Clone:

LBI2H6

Conjugation:

Unconjugated

Gene name:

syndecan binding protein

Symbol:

SDCBP

Pathway:

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Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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