Product overview:

DOK7 mouse monoclonal antibody, clone LBI5C6

Field of research:

Request info at info@sobekbio.com

Summary:

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Alternative names:

C4orf25; CMS1B; CMS10

Species reactivity:

Human

Host:

Mouse

Target:

DOK7

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human DOK7(NP_775931) produced in HEK293T cell.

Clone:

LBI5C6

Conjugation:

Unconjugated

Gene name:

docking protein 7

Symbol:

DOK7

Pathway:

Request info at info@sobekbio.com

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.84 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com