Product overview:

PPAT mouse monoclonal antibody, clone LBI1B11

Field of research:

Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism

Summary:

The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]

Alternative names:

ATASE; GPAT; PRAT

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PPAT

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 42-278 of human PPAT(NP_002694) produced in E.coli.

Clone:

LBI1B11

Conjugation:

Unconjugated

Gene name:

phosphoribosyl pyrophosphate amidotransferase

Symbol:

PPAT

Pathway:

Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism

Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com