Product overview:

ATIC mouse monoclonal antibody, clone LBI4A10

Field of research:

Metabolic pathways, One carbon pool by folate, Purine metabolism

Summary:

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]

Alternative names:

AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH

Species reactivity:

Human, Mouse, Rat, Dog

Host:

Mouse

Target:

ATIC

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell.

Clone:

LBI4A10

Conjugation:

Unconjugated

Gene name:

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

Symbol:

ATIC

Pathway:

Metabolic pathways, One carbon pool by folate, Purine metabolism

Function:

Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

3.51 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~1000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com