Product overview:

HLCS mouse monoclonal antibody, clone LBI1E4

Field of research:

Biotin metabolism, Metabolic pathways

Summary:

This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names:

HCS

Species reactivity:

Human

Host:

Mouse

Target:

HLCS

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human HLCS(NP_000402) produced in HEK293T cell.

Clone:

LBI1E4

Conjugation:

Unconjugated

Gene name:

holocarboxylase synthetase

Symbol:

HLCS

Pathway:

Biotin metabolism, Metabolic pathways

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com