Product overview:

SPG7 mouse monoclonal antibody, clone LBI1E5

Field of research:

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Summary:

This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq]

Alternative names:

CAR; CMAR; PGN; SPG5C

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SPG7

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragement corresponding to amino acids 300-573 of human SPG7(NP_003110) produced in E.coli.

Clone:

LBI1E5

Conjugation:

Unconjugated

Gene name:

SPG7 matrix AAA peptidase subunit, paraplegin

Symbol:

SPG7

Pathway:

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Function:

Protease, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.74 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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