Product overview:

ACD mouse monoclonal antibody, clone LBI1A2

Field of research:

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Summary:

This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq]

Alternative names:

PIP1; PTOP; TINT1; TPP1

Species reactivity:

Human

Host:

Mouse

Target:

ACD

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ACD(NP_001075955) produced in HEK293T cell.

Clone:

LBI1A2

Conjugation:

Unconjugated

Gene name:

ACD shelterin complex subunit and telomerase recruitment factor

Symbol:

ACD

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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