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Specifications
| 20 Tests / 50 Tests / 100 Tests |
Background:
CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
Alternative names:
Integrin alpha-E,Itgae,Integrin alpha M290,CD103
Description:
Antibody for flow cytometry
Species reactivity:
Mouse
Host:
Rat
Isotype:
Rat IgG2a, κ
Concentration:
Request info at info@sobekbio.com
Buffer:
PBS with 0.05% Proclin300, 1% BSA
Conjugation:
AF647
Applications:
FCM
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com