Background:

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Alternative names:

T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7

Description:

Antibody for flow cytometry

Species reactivity:

Mouse

Host:

Armenian Hamster

Isotype:

Armenian Hamster IgG

Concentration:

Request info at info@sobekbio.com

Buffer:

PBS with 0.05% Proclin300, 1% BSA

Conjugation:

PE/TR

Applications:

FCM

Storage:

Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com