FITC Anti-Mouse CD45R/B220 Antibody DL21363F
Specifications
| 50 Tests / 100 Tests / 500 Tests |
Background:
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Alternative names:
B220
Description:
Antibody for flow cytometry
Species reactivity:
Mouse
Host:
Rat
Isotype:
Rat IgM, κ
Concentration:
Request info at info@sobekbio.com
Buffer:
PBS with 0.05% Proclin300, 1% BSA
Conjugation:
FITC
Applications:
FCM
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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