PE Anti-Human CD45 Antibody DL20583F
Specifications
| 20 Tests / 50 Tests / 100 Tests |
Background:
CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Alternative names:
Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45
Description:
Antibody for flow cytometry
Species reactivity:
Human
Host:
Mouse
Isotype:
Mouse IgG2a, κ
Concentration:
Request info at info@sobekbio.com
Buffer:
PBS with 0.05% Proclin300, 1% BSA
Conjugation:
PE
Applications:
FCM
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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