Background:

This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.

Classification:

Primary antibody

Alternative names:

CDH5

Species reactivity:

Human,Rat,Mouse

Host:

Mouse

Isotype:

IgG

Immunogen:

Synthetic Peptide of VE-Cadherin at AA range of 670-750

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

IHC-p, IF

Storage:

-20°C for one year

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