Background:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i

Classification:

Primary antibody

Alternative names:

TGFB1

Species reactivity:

Rat,Mouse

Host:

Mouse

Isotype:

IgG

Immunogen:

Synthetic Peptide of TGFBeta1 at AA range of 310-390

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

IHC-p, IF

Storage:

-20°C for one year

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