Rb Monoclonal Antibody BT-MCA1094
Specifications
| 50ul / 100ul |
Background:
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Classification:
Primary antibody
Alternative names:
RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
Species reactivity:
Human
Host:
Mouse
Isotype:
IgG
Immunogen:
Purified recombinant fragment of human Rb expressed in E. Coli.
Concentration:
1 mg/ml
Molecular weight:
N/A
Applications:
IHC-p, IF, ELISA
Storage:
-20°C for one year
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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