Background:

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

Classification:

Primary antibody

Alternative names:

ZBTB16; PLZF; ZNF145; Zinc finger and BTB domain-containing protein 16; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; Zinc finger protein PLZF

Species reactivity:

Human

Host:

Mouse

Isotype:

IgG

Immunogen:

Purified recombinant fragment of human PLZF expressed in E. Coli.

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

WB, IF, ICC, ELISA

Storage:

-20°C for one year

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