Background:

The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

Next to BRCA1 gene 1 protein; Cell migration-inducing gene 19 protein; Membrane component chromosome 17 surface marker 2; Neighbor of BRCA1 gene 1 protein; Protein 1A1-3B

Species reactivity:

Human,Mouse,Rat

Host:

Mouse

Isotype:

IgG

Immunogen:

Recombinant Protein of NBR1

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

IF, ICC, IHC-p

Storage:

-20°C for one year

More info:

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