Background:

This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

LPP; Lipoma-preferred partner; LIM domain-containing preferred translocation partner in lipoma

Species reactivity:

Human,Mouse,Monkey,Hamster

Host:

Mouse

Isotype:

IgG

Immunogen:

Purified recombinant fragment of human LPP expressed in E. Coli.

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

WB, IHC-p, IF, ICC, ELISA

Storage:

-20°C for one year

More info:

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