Background:

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.

Classification:

Primary antibody

Alternative names:

DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3

Species reactivity:

Human,Monkey

Host:

Mouse

Isotype:

IgG

Immunogen:

Purified recombinant fragment of human Dkk-3 expressed in E. Coli.

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

WB, FCM, ELISA

Storage:

-20°C for one year

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