Background:

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Classification:

Primary antibody

Alternative names:

Collagen alpha-1(II) chain; Alpha-1 type II collagen

Species reactivity:

Human,Mouse,Rat

Host:

Mouse

Isotype:

IgG

Immunogen:

Synthetic Peptide of Collagen II

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

IHC-p, IF

Storage:

-20°C for one year

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