Background:

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Classification:

Primary antibody

Alternative names:

PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin

Species reactivity:

Human,Rat,Mouse

Host:

Mouse

Isotype:

IgG

Immunogen:

Synthetic Peptide of PCNA

Concentration:

1 mg/ml

Molecular weight:

28769

Applications:

WB, IF, ICC, IHC-p

Storage:

-20°C for one year

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