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"Croyez" specializes in bringing scientists "absolute solution" products for all applications of the protein research area. They offer recombinant protein GMP and RUO grade, mRNA synthesis raw material, Molecular Diagnosis raw material, Allergen raw material, COVID -19 antibody and antigen and Later flow products. Every tool you need to fulfill your research experiment in the protein area, Croyez has relevant products to offer. They also provide CRO/CDMO service, customize protein production, customize monoclonal antibody production, customize immunoassay platform and Diagnosis platform development.
Anti-Covid-19 Spike mAb IgG(05FC) BT-CV00005
Specifications
| 100ug / 1mg |
Background:
Coronaviruses (CoVs) infect human and animals and cause varieties of diseases, including respiratory, enteric, renal, and neurological diseases. CoV uses its spike protein to recognize ACE2 as its receptors and mediate membrane fusion and virus entry into host cells(PMID: 32221306). Each monomer of trimeric S protein is about 180 kDa, and contains two subunits, S1 and S2,S1 recognizes and binds to host receptors, and subsequent conformational changes in S2 facilitate fusion between the viral envelope and the host cell membrane(PMID: 19198616). Although the amino acid sequences of the S-glycoprotein were found to be different between the various HCoV, the structures showed high similarity, but the best 3D structural overlap shared by SARS-CoV and SARS-CoV-2, consistent with the shared ACE2 predicted receptor (PMID: 32522207). The spike protein of CoVs can be a target for vaccine and therapeutic development (PMID: 19198616).
Classification:
Secondary antibody
Alternative names:
SARS-CoV-2 Spike, 2019-nCoV Spike, Covid-19 Spike
Species reactivity:
Covid-19
Host:
Mouse
Isotype:
IgG
Immunogen:
The recombinant SARS-CoV-2 (2019-nCoV) Spike Protein S
Concentration:
2mg/mL
Molecular weight:
Applications:
WB,ELISA
Storage:
-20°C for 1 year
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com