TGF beta RII(Phospho Ser225) Polyclonal Antibody BT-AP14906
Specifications
| 20ul / 50ul / 100ul |
Background:
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Classification:
Primary antibody
Alternative names:
TGF-beta receptor type-2; TGFBR2; TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II
Species reactivity:
Human, Mouse
Host:
Rabbit
Isotype:
IgG
Immunogen:
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225/250. AA range:191-240
Concentration:
1 mg/ml
Molecular weight:
64568
Applications:
IHC-p, IF, ELISA
Storage:
-20°C for 1 year
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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