Pim-1(Phospho Tyr309) Polyclonal Antibody BT-AP13051
Specifications
| 20ul / 50ul / 100ul |
Background:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).
Classification:
Primary antibody
Alternative names:
Serine/threonine-protein kinase pim-1; PIM1; Serine/threonine-protein kinase pim-1
Species reactivity:
Human, Mouse, Rat
Host:
Rabbit
Isotype:
IgG
Immunogen:
The antiserum was produced against synthesized peptide derived from human Pim-1 around the phosphorylation site of Tyr309. AA range:281-330
Concentration:
1 mg/ml
Molecular weight:
45412
Applications:
WB, ELISA
Storage:
-20°C for 1 year
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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