NR1H2 Polyclonal Antibody BT-AP12006
Specifications
| 20ul / 50ul / 100ul |
Background:
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009
Classification:
Primary antibody
Alternative names:
Oxysterols receptor LXR-beta ;Liver X receptor beta;Nuclear receptor NER;Nuclear receptor subfamily 1 group H member 2;Ubiquitously-expressed nuclear receptor
Species reactivity:
Human, Rat, Mouse
Host:
Rabbit
Isotype:
IgG
Immunogen:
Synthesized peptide derived from part region of human protein
Concentration:
1 mg/ml
Molecular weight:
Applications:
WB, ELISA
Storage:
-20°C for 1 year
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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