DOCK 2 Polyclonal Antibody BT-AP02693
Specifications
| 20ul / 50ul / 100ul |
Background:
Dedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection.
Classification:
Primary antibody
Alternative names:
DOCK2; KIAA0209; Dedicator of cytokinesis protein 2
Species reactivity:
Human;Mouse;Rat
Host:
Rabbit
Isotype:
IgG
Immunogen:
Synthesized peptide derived from the Internal region of human DOCK 2.
Concentration:
1 mg/ml
Molecular weight:
211948
Applications:
IHC-p, ELISA
Storage:
-20°C for one year
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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