Background:

DRD4 encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in DRD4 have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. DRD4 contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Classification:

Primary antibody

Alternative names:

DRD4; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human DRD4. AA range:355-404

Concentration:

1 mg/ml

Molecular weight:

48361

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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