Background:

DRD3 encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Classification:

Primary antibody

Alternative names:

DRD3; D(3) dopamine receptor; Dopamine D3 receptor

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from D3DR . at AA range: 181-230

Concentration:

1 mg/ml

Molecular weight:

44225

Applications:

WB, ELISA

Storage:

-20°C for one year

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