Background:

CYP26A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of CYP26A1, which encode the distinct isoforms, have been reported.

Classification:

Primary antibody

Alternative names:

CYP26A1; CYP26; P450RAI1; Cytochrome P450 26A1; Cytochrome P450 retinoic acid-inactivating 1; Cytochrome P450RAI; hP450RAI; Retinoic acid 4-hydroxylase; Retinoic acid-metabolizing cytochrome

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Cytochrome P450 26A1. AA range:251-300

Concentration:

1 mg/ml

Molecular weight:

56163

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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