Background:

COL7A1 encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Classification:

Primary antibody

Alternative names:

COL7A1; Collagen alpha-1(VII) chain; Long-chain collagen; LC collagen

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Collagen VII alpha1. AA range:1841-1890

Concentration:

1 mg/ml

Molecular weight:

295220

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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