Background:

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for CDC25A.

Classification:

Primary antibody

Alternative names:

CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CDC25A. AA range:90-139

Concentration:

1 mg/ml

Molecular weight:

59087

Applications:

WB, ELISA

Storage:

-20°C for one year

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