Background:

CD2BP2 encodes a bi-functional protein (CD2 cytoplasmic tail binding protein 2). In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Classification:

Primary antibody

Alternative names:

CD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2

Species reactivity:

Human;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150

Concentration:

1 mg/ml

Molecular weight:

37646

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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