Background:

C8B (complement C8 beta chain) encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

Complement component C8 beta chain (Complement component 8 subunit beta)

Species reactivity:

Human;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420

Concentration:

1 mg/ml

Molecular weight:

67047

Applications:

WB, ELISA

Storage:

-20°C for one year

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