Background:

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.

Classification:

Primary antibody

Alternative names:

ARL2BP; BART; BART1; ADP-ribosylation factor-like protein 2-binding protein; ARF-like 2-binding protein; Binder of ARF2 protein 1

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ARL2BP. AA range:101-150

Concentration:

1 mg/ml

Molecular weight:

18822

Applications:

WB, ELISA

Storage:

-20°C for one year

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