Background:

ABCC12 is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein (ATP binding cassette subfamily C member 12) contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes.ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. ABCC12 is a member of the MRP subfamily which is involved in multi-drug resistance. ABCC12 and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of ABCC12 is associated with breast cancer.

Classification:

Primary antibody

Alternative names:

ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MRP9. AA range:691-740

Concentration:

1 mg/ml

Molecular weight:

152297

Applications:

WB, ELISA

Storage:

-20°C for one year

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