Background:

Acyl-CoA synthetases(ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage(By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids(By similarity). It was suggested that it may also stimulate fatty acid oxidation(By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

ACS2, ACS5, ACSL5, FACL5, LACS 5

Specificity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

acyl-CoA synthetase long-chain family member 5

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

76 kDa

Form:

liquid

Applications:

ELISA, WB, IP

Recommended dilution:

WB: 1:500-1:5000; IP: 1:200-1:2000

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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