Background:

ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

ACACA Synonyms ACAC, ACACA, ACC, ACC1, ACCA, Acetyl CoA carboxylase 1

Specificity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

acetyl-Coenzyme A carboxylase alpha

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

270 kDa

Form:

liquid

Applications:

ELISA, WB, IHC, IP, IF

Recommended dilution:

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200; IP: 1:200-1:2000

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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