Background:

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

FIP3, NEMO

Specificity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

40-55 kDa

Form:

liquid

Applications:

ELISA, WB

Recommended dilution:

WB: 1:500 - 1:2000

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

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