Fine Biotech is an ISO9001:2008 Certified Company,offers a full line of quality research kits,which include ELISA Kits,related ELISA assistant reagents and more high quality antibodies, recombinant proteins. Fine Biotech technical support are delicated to providing with professional and friendly assistance for our customers. Strict and multiple quality control ensure that our products continue to successfully supply for the international market. Moreover, we strive to continuously improve the customer experience through comprehensive technical support. High quality,rapid turnaround and personal support for all FineTest services are guaranteed. Should you have any problems,or any ideas on ways that we can improve our service,please feel free to call upon us.Thank you for your interest in FineTest products and we look forward to supplying you in the near future.Human FLT1 Protein, His Tag PME100726
Specifications
| 10µg / 50µg / 100µg |
Alternative names:
VEGFR-1;Tyrosine-protein kinase FRT;FLT-1;FLT;Vascular permeability factor receptor
Description:
Recombinant human FLT1 protein with C-terminal 6×His tag
Background:
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
Molecular characterization:
FLT1(Ser27-Asn756) 6×His tag
Molecular weight:
The protein has a predicted molecular mass of 83.0 kDa after removal of the signal peptide. The apparent molecular mass of FLT1-His is approximately 100-130 kDa due to glycosylation.
Tag:
C-6×His Tag
Expression host:
HEK293
Target:
FLT1
Purity:
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation / Reconstitution:
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
More info:
Email info@sobekbio.com
Orders:
Email orders@sobekbio.com