Alternative names:

CBP35;GAL3;GALBP;GALIG;L31;LGALS2;MAC2

Description:

Recombinant Human LGALS3 Protein with C-terminal 6×His tag

Background:

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]

Molecular characterization:

LGALS3(Ala2-Ile250) 6×His Tag

Molecular weight:

The protein has a predicted molecular mass of 26.9 kDa after removal of the signal peptide.The apparent molecular mass of LGALS3-His is approximately 25-35 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

LGALS3

Purity:

The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com