Alternative names:

B1;Bp35;CD20;CVID5;LEU-16;MS4A2;S7

Description:

Recombinant Human CD20 protein with N-terminal human Fc

Background:

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.

Molecular characterization:

hFc(Glu99-Ala330) CD20(Lys142-Ser188)

Molecular weight:

The protein has a predicted molecular mass of 31.6 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CD20 is approximately 35-55 kDa due to glycosylation.

Tag:

N-Human Fc Tag

Expression host:

HEK293

Target:

CD20

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com