Alternative names:

MIC-B;PERB11.2

Description:

Recombinant Human MICB Protein with C-terminal 6×His tag

Background:

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Molecular characterization:

MICB(Ala23-Asp309) 6×His tag

Molecular weight:

The protein has a predicted molecular mass of 33.5 kDa after removal of the signal peptide.The apparent molecular mass of MICB-His is approximately 35-55 kDa due to glycosylation.

Tag:

C-6×His Tag

Expression host:

HEK293

Target:

MICB

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com