Fine Biotech is an ISO9001:2008 Certified Company,offers a full line of quality research kits,which include ELISA Kits,related ELISA assistant reagents and more high quality antibodies, recombinant proteins. Fine Biotech technical support are delicated to providing with professional and friendly assistance for our customers. Strict and multiple quality control ensure that our products continue to successfully supply for the international market. Moreover, we strive to continuously improve the customer experience through comprehensive technical support. High quality,rapid turnaround and personal support for all FineTest services are guaranteed. Should you have any problems,or any ideas on ways that we can improve our service,please feel free to call upon us.Thank you for your interest in FineTest products and we look forward to supplying you in the near future.Anti -HMGB1 Mouse mAb GB12103
Specifications
| 100 µL |
Alternative names:
HMGB1,HMG1,HMG3,SBP-1,HMG-1
Product info:
HMGB1 mouse monoclonalProtein full nameHigh mobility group protein B1SynonymsHMGB1, HMG1, HMG3, SBP-1, HMG-1, high mobility group box 1ImmunogenKLH conjugated Synthetic peptidecorresponding to Mouse HMGB1IsotypeIgGPurityAffinity purificationSubcellular locationNucleus. Chromosome. Cytoplasm. Secreted. Cell membrane. Endosome.Uniprot IDP09429, P63158, P63159ApplicationsApplicationsSpeciesDilutionPositive TissueIHC, IFHuman1:200-1:1000lymphomaBackgroundLike the histones, HMGB1 is among the most important chromatin proteins. In the nucleus HMGB1 interacts withnucleosomes, transcription factors, and histones. This nuclear protein organizes the DNA and regulates transcription.After binding, HMGB1 bendsDNA, which facilitates the binding of other proteins. HMGB1 supports transcription of many genes in interactions with many transcription factors. It also interacts with nucleosomes to loosen packed DNA and remodel the chromatin. Contact with core histones changes the structure of nucleosomes.ImagesImmunohistochemistry analysis of paraffin-embedded human lymphoma using HMGB1 (GB12103) at dilution of 1: 1000StorageStorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.NOTE: 1.This product is intended for research only.2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
More info:
Email info@sobekbio.com
Orders:
Email orders@sobekbio.com