Alternative names:

CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1

Description:

Human S1PR1 full length protein-synthetic nanodisc

Background:

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Protein families:

GPCR,Transmembrane,Druggable Genome,

Protein pathways:

GPCRDB Other,S1P Signaling,Small ligand GPCRs,Angiogenesis,Angiogenesis,G-Protein Coupled Receptors Signaling Pathway,

Expression host:

HEK293

Target:

S1PR1

Molecular weight:

The human full length S1PR1 protein has a MW of 42.8kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com