Alternative names:

GALNR, GALNR1

Description:

Human GALR1 full length protein-synthetic nanodisc

Background:

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]

Protein families:

Transmembrane,Druggable Genome,

Protein pathways:

GPCRDB Class A Rhodopsin-like,Peptide GPCRs,Metabolic and Obesity,

Expression host:

HEK293

Target:

GALR1

Molecular weight:

The human full length GALR1 protein has a MW of 39kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com