Alternative names:

GABABR1, GABBR1-3, GB1, GPRC3A

Description:

Human GABR1 full length protein-synthetic nanodisc

Background:

This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016]

Protein families:

GPCR,Secreted,Transmembrane,Druggable Genome,

Protein pathways:

GPCRDB Class C Metabotropic glutamate pheromone,

Expression host:

HEK293

Target:

GABR1

Molecular weight:

The human full length GABR1 protein has a MW of 108.3kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com