Alternative names:

Fz-3

Description:

Human FZD3 full length protein-synthetic nanodisc

Background:

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]

Protein families:

GPCR,Transmembrane,Druggable Genome,

Protein pathways:

Wnt signaling,Wnt signaling and pluripotency,Cancer,Notch,Wnt Pathway,Stem Cell ,

Expression host:

HEK293

Target:

FZD3

Molecular weight:

The human full length FZD3 protein has a MW of 76.3kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com