Alternative names:

'-

Description:

Human FZD1 full length protein-synthetic nanodisc

Background:

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008]

Protein families:

GPCR,Transmembrane,Druggable Genome,

Protein pathways:

Adipogenesis,Wnt NetPath 8,Wnt signaling,Wnt signaling and pluripotency,Cancer,Notch,Wnt Pathway,Stem Cell ,

Expression host:

HEK293

Target:

FZD1

Molecular weight:

The human full length FZD1 protein has a MW of 71.2kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com