Alternative names:

——

Description:

Human GPR20 full length protein-synthetic nanodisc

Background:

GPR20 is one of the orphan GPCRs that has been identified from human genomic DNA by PCR amplification using primers based on the sequences of the opioid/somatostatin-related receptors, GPR7 and GPR8. The expression of human GPR20 has been detected in several brain regions, including the caudate nuclei, putamen, and the thalamus. A recently disclosed patent demonstrated that GPR20-deficient mice exhibited a hyperactivity disorder characterized by an increase in total distance traveled in an open field test, implying a substantial role of GPR20 in neurophysiological function. However, the physiological mechanisms of GPR20 action, including the identification of natural ligands for GPR20, have not yet been elucidated.

Protein families:

Druggable Genome, GPCR, Transmembrane

Protein pathways:

N/A

Expression host:

HEK293

Target:

GPR20

Molecular weight:

The human full length GPR20 protein has a MW of 38.7 kDa

Formulation / Reconstitution:

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0).  Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Usage:

Research use only

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com